Substance Use

Should Benzodiazepines Be Used Long Term? What the Research Says

If you've been on a benzodiazepine for months or years and you're starting to wonder if that's still a good idea, you're asking the right question — here's what long-term use actually does.

October 12, 20267 min readbenzodiazepineslong-term usewithdrawal
Peter Scheid, MD

Medically reviewed by Peter Scheid, MD

Medical Director, SILC Health

Alexandra Truman, LMFT

Clinically reviewed by Alexandra Truman, LMFT

Clinical Director, Substance Use Services — SILC Health

Last reviewed: June 16, 2026

Maybe a doctor started you on a benzodiazepine (a class of anti-anxiety and sedative medications like Xanax, Valium, or Ativan) after a panic attack, a bad bout of insomnia, or a stressful season of life — and now, a year or more later, you're still taking it and wondering if that's actually okay. You're not alone in asking, and you're not doing anything wrong by questioning it. The short answer: most clinical guidance, including FDA prescribing information, supports benzodiazepines for short-term use — typically a few weeks — not indefinite daily use, because the risks of tolerance, dependence, and withdrawal climb the longer someone stays on them.

What Counts as "Long-Term" Benzodiazepine Use?

There's no single magic cutoff, but FDA labeling for most benzodiazepines prescribed for anxiety recommends treatment durations measured in weeks, not months or years. If you've been taking one daily for six months, a year, or longer — even exactly as prescribed — you're in territory where your body has likely adapted to the medication in ways that make stopping more complicated than just skipping a dose.

What Long-Term Use Can Do to the Body and Brain

This isn't about blame. Benzodiazepines work by enhancing a calming brain chemical called GABA (gamma-aminobutyric acid, the brain's main 'slow down' signal), and over time the brain adjusts to that constant presence. According to the National Institute on Drug Abuse (NIDA), long-term benzodiazepine use can lead to tolerance (needing more of the drug to get the same effect) and physical dependence (the body adapting so that stopping causes withdrawal symptoms), even when the medication is taken exactly as prescribed.

  • Tolerance — needing a higher dose over time for the same anxiety or sleep relief
  • Physical dependence — the brain and body adjusting to expect the drug, independent of any misuse
  • Cognitive effects — many people report memory and concentration changes with extended use
  • Interaction risk — CDC data shows benzodiazepines are frequently involved in overdose deaths, particularly when combined with opioids or alcohol
  • Withdrawal risk if stopped abruptly, which can range from rebound anxiety to medically serious symptoms

Why You Can't Just Stop — And Why That's Not a Character Flaw

If you've tried to quit on your own and ended up more anxious, shaky, or unable to sleep than before you started the medication, that's not a sign you're weak or broken. That's your nervous system reacting to the sudden absence of a chemical it had adapted around. This is exactly why benzodiazepine withdrawal is handled differently than many other substances — the body needs time, and sometimes medical support, to recalibrate.

Signs It Might Be Time for a Different Approach

  • You've needed to increase your dose, or you're taking more than prescribed, to feel the same effect
  • You've tried to cut back or stop and felt withdrawal symptoms you weren't prepared for
  • You're mixing the benzodiazepine with alcohol or other medications to feel okay
  • You feel like you can't function — or can't sleep, or can't calm down — without it anymore
  • A family member or partner has mentioned they're worried about how much you're taking

If any of that sounds familiar, it's worth a conversation with someone who does this work every day. We get calls like this all the time — from people who were following their doctor's instructions and still ended up dependent, and from people who know their use has drifted past what's safe. There's no judgment on these calls. If you want to talk through what you're experiencing and what your options actually look like, call (844) 422-8640. It's a no-pressure conversation — we're here to listen first.

What Benzodiazepine Treatment Actually Looks Like

Because benzodiazepine withdrawal can carry real medical risk, the safest starting point for most people who've used them long-term is a structured, supervised taper rather than quitting cold. Facilities like Cove Detox, Leucadia Detox, Seaside Detox, and Harbor Detox are DHCS-licensed detox programs offering ASAM Level 3.5 clinically managed detox with medical supervision (ASAM is the national clinical framework used to match treatment intensity to a person's needs) — meaning nursing assessments and physician-directed medication management guide the taper rather than leaving someone to manage it alone.

For people who need a higher level of structure during and after detox, Riverfront Recovery Center in Hiawassee, Georgia, licensed by the Georgia Department of Community Health, offers ASAM Level 3.5 residential treatment with on-site residential sub-acute detox and 24/7 nursing.

Once the acute withdrawal period has passed, many people step down to outpatient-level care to work on the anxiety, insomnia, or trauma that led to benzodiazepine use in the first place. Southern California Recovery Centers in Carlsbad offers a DHCS-licensed men's PHP/IOP program (partial hospitalization and intensive outpatient — structured treatment during the day while living at home or in sober housing) using evidence-based approaches like CBT (cognitive behavioral therapy, which helps identify and change unhelpful thought patterns). For people whose anxiety or other mental health symptoms need more intensive, round-the-clock support after stabilization, One Path Mental Health provides residential mental health treatment under a CDSS license with DHCS certification.

Paying for Care With Your Employer Health Plan

If you have a PPO-style plan (a type of employer-sponsored insurance that typically includes out-of-network benefits) through your job, you likely have more coverage options than you realize — including for care outside your plan's network. A lot of people hesitate to look into treatment because they assume their employer will find out, but verifying benefits is a private conversation between you, us, and your insurance company. Our admissions team can check your out-of-network and in-network benefits before you commit to anything, so you know what's realistically covered before you make a decision.

Taking the Next Step

You don't have to have this figured out before you call. You don't need a diagnosis, a plan, or even certainty that you want to stop — you just need a reason to pick up the phone. Call (844) 422-8640 and we'll talk through what you're dealing with, what level of care might make sense, and what it could look like to taper safely instead of white-knuckling it alone. No pressure, no obligation — just a conversation.

People also ask

Common questions.

Is it dangerous to suddenly stop taking a benzodiazepine after long-term use?

Yes, it can be. The FDA's boxed warning on benzodiazepines specifically flags withdrawal reactions, which in some cases include seizures, after long-term use. If you've been taking a benzodiazepine daily for months or longer, any reduction in dose should happen under medical supervision rather than on your own.

Can someone become dependent on a benzodiazepine even if they took it exactly as prescribed?

Yes. According to NIDA, physical dependence can develop from long-term benzodiazepine use regardless of whether the medication was taken exactly as a doctor directed. Dependence isn't the same as misuse — it's a physical adaptation, and it's one of the main reasons benzodiazepines are generally recommended only for short-term use.

What's the difference between detox and residential treatment for benzodiazepine use?

Detox focuses on the first phase — safely managing withdrawal through nursing assessments and physician-directed medication management, which is what facilities like Cove Detox, Leucadia Detox, Seaside Detox, and Harbor Detox provide. Residential treatment, like what's offered at Riverfront Recovery Center, builds on that with structured, round-the-clock care that can include therapy and longer-term stabilization after the physical withdrawal period.

Will my employer find out if I call about benzodiazepine treatment?

No — verifying your insurance benefits and talking with our admissions team is a private process between you and us. If you have a PPO-style employer plan, we can check your out-of-network benefits confidentially before you decide on anything, and that conversation stays between you and your insurance carrier.

What if I've been taking more of my prescription than I was supposed to?

That's a more common situation than people think, and it's one we talk through with callers regularly without judgment. Taking more than prescribed can mean your body has built tolerance, which is worth discussing with a treatment team so any tapering plan accounts for your actual usage pattern, not just the original prescription.

Can therapy help after I'm off a benzodiazepine, or is the medication taper the whole process?

The taper is usually just the first part. Many people used benzodiazepines originally for anxiety, panic, or insomnia, and evidence-based approaches like CBT (cognitive behavioral therapy) in a PHP or IOP program can address those underlying issues so there's less pull to rely on the medication again.

Talk to admissions

Ready when you are.

One call confirms benefits, walks through what arrival looks like, and sets a clear plan from wherever you're starting.

(844) 422-8640